TTA IC 1st International Conference

30th AESF

30. Arbeitstagung Experimentelle Schilddrüsenforschung / December 4-5, 2014 / Jacobs University Bremen

Programm / Program:

Thursday,   4th December, 2014

15:00     Welcome / Opening: Klaudia Brix, Bremen & Josef Köhrle, Berlin

Session 1 New TH Metabolites in Central and Systemic Communication

Chairpersons: Josef Köhrle, Berlin & Annika Herwig, Hamburg

15:15 – 16:00    Jens Mittag, Lübeck: How to distinguish central from peripheral effects of TH and their metabolites

16:00 – 16:15    Jonathan Bank, Hamburg: Influence of thyroid hormones on daily torpor and gene expression in Djungarian hamsters (Phodopus sungorus)

16:15 – 16:30    Susanne Giersiefer, Düsseldorf: Species-specific effects of thyroid hormone on neuro-developmental processes in vitro

16:30 – 16:45    Franziska Meyer, Berlin: Cell type-specific inactivation of Mct8 in brain cells: Gene expression, metabolism

16:45 – 17:00    Steffen Mayerl, Jena: Analysis of neuromuscular function in Mct8/Oatp1c1 dko mice

17:00 – 17:15     Coffee Break

17:15 – 17:30    Alice Accorroni, Pisa, Italia: Cerebrospinal fluid levels of T4, T3 and rT3 in patients with dementia

17:30 – 17:45    Noushafarin Khajavi, Berlin: Association between direct interaction of thyronamine with TRPM8 and suppression of TRPV1 activity in a human conjunctival epithelial cell line (IOBA-NHC)

17:45 – 18:00    Irmgard Dietzel-Meyer, Bochum: Thyroid hormone effects on metabolic rate can be explained by an up-regulation of sodium currents induced by growth factors released from glial cells in postnatal rat brain

18:00 – 18:15    Till Ittermann, Greifswald: High TSH is Associated with Aortic Wall Thickness in the General Population

18:15 – 19:00     Dinner

Session 2 – Endocrine Disruptors & Novel Techniques

Chairperson: Gunnar Kleinau, Berlin

19:00 – 19:45    Gina Montoya, Ludwigshafen: Endocrine disrupters of the thyroid hormone axis: Metabolism and metabolomics

19:45 – 20:00    Daniel Rathmann, Berlin: Determination of Thyroid Hormones via LC-MS/MS

20:00 – 20:15    Roopa Naidu, Berlin: Novel Non-Radioactive Assay allowing Rapid Studies on Substrate-Uptake by selected Thyroid Hormone Transporters

20:15     Get-together at “T.O.S. – The Other Side” (Music Lab), Jacobs University

Friday, 5th December 2014

Session 3 – TH, Metabolism, Aging & Sex

Chairpersons: Jessica Mühlhaus, Berlin & Maria Faassen, Moscov

08:45 – 09:30    Robert Ringseis & Klaus Eder, Giessen: The role of sterol regulatory element-binding proteins in the regulation of NIS and TPO – a novel regulatory pathway of thyroid hormone synthesis

09:30 – 09:45    Julika Lietzow, Berlin: Effects of the thyroid hormone metabolite 3,5-T2 in lean and obese mice

09:45 – 10:00    Helena Rakov, Essen: Influence of sex on thyroid hormone action in mice

10:00 – 10:15     Anna Dresler, Berlin: The influence of thyroid hormones on cellular energy metabolism and steroidogenic enzyme mRNA expression in murine Leydig tumor cell line-1

10:15 – 10:30    Kathrin Engels, Essen: Molecular mechanisms of age-dependent thyroid hormone action in target tissues

10:30 – 10:45     Coffee Break

Session 4 – Novel Pathways of TH Signaling & Action

Chairpersons: Denise Zwanziger, Essen & Georg Homuth, Greifswald

10:45 – 11:30    Renate B. Pilz, San Diego: TH signaling via plasma membrane receptors

11:30 – 11:45    Sebastian Hönes, Essen: TR-mediated non-classical thyroid hormone action

11:45 – 12:00    Kathrin Schmohl, München: Effect of thyroid hormones T3 and T4 on mesenchymal stem cell biology

12:00 – 12:15    Nancy Schanze, Berlin: Effects of 3-Iodothyronamine (3-T1AM) on thyrocytes

12:15 – 12:30    Claudia Stäubert, Leipzig: Does 3-iodothyronamine activate receptors of the trace amine-associated receptor family, other than TAAR1?

12:30 – 12:45    Jessica Mühlhaus, Berlin: 3-iodothyronamine differentially modulates alpha-2A adrenergic receptor-mediated signaling

12:45 – 13:30     Lunch

Session 5 – Thyroid Cancer, TH Transport & Stem Cells

Chairpersons: Heike Heuer, Düsseldorf & Joanna Szumska, Bremen

13:30 – 13:45    Sören Latteyer, Essen: Novel insights into RET pathway activation in a MEN2 patient

13:45 – 14:00    Andrea Müller, München: In vivo imaging of mesenchymal stem cell recruitment into the tumor stroma of hepatocellular carcinoma (HCC) using a HIF1-specific sodium iodide symporter gene system

14:00 – 14:15    Jörg Johannes, Berlin: Targeted mutations in MCT10 expand the substrate spectrum to include T4

14:15 – 14:30    Katrin M. Hinz, FMP Berlin: Lat2: Structure function analysis of transport mechanisms and of thyroid hormone like substrate characteristics

14:30 – 14:45     Coffee Break

14:45 – 15:00    Jana Fischer, Berlin: Identification of new Interaction Partners of TSHR

15:00 – 15:15    Maren Rehders, Bremen: Mouse thyroid cysteine cathepsins in hypo- and hyperthyroidism

15:15 – 15:30    Jonas Weber, Bremen: Phenotyping of the mouse thyroid gland by automated image analysis

15:30 – 15:45    Julia Badziong, Essen: TH transporters in thyroid tumorigenesis

15:45 – 16.30    Ulrich Schweizer & Doreen Braun, Bonn: Influencing TH Transport by Tyrosine Kinase Inhibitors and Other Drugs

16:30 – 16:45     Travel Awards & AESF 2014 Closure

Organization: / Organisation:

Klaudia Brix, Jacobs University Bremen ~

Josef Köhrle, Charité Universitätsmedizin Berlin

Team Assistant Sabine Meier ~

The 30th AESF is supported by


Bayer sanofi Thermo
Genzyme AstraZeneca NVS_Onc RGB
Ipsen Pharma DGE_Logo Sobi
BASF ME_R_4C_100